•  

    Proven results, fast

    Advanced Joint Liquid

    The Gold Standard of joint care, formulated with UC-II Collagen©†clinically proven to reduce discomfort in just 30 days.

Proven results, fast

Advanced Joint Liquid

The Gold Standard of joint care, formulated with UC-II Collagen©†clinically proven to reduce discomfort in just 30 days.

Shop Now

✓ No Artificial Colors or Flavors

✓ GMP/SOF Certified

✓ In line with FDA CVM Guidelines

✓ Batch Tested

✓ Made in USA with Globally Sourced Ingredients

✓ Formulated by Pet Scientists

✓ No Artificial Colors or Flavors

✓ GMP/SOF Certified

✓ In line with FDA CVM Guidelines

✓ Batch Tested

✓ Made in USA with Globally Sourced Ingredients

✓ Formulated by Pet Scientists

✓ No Artificial Colors or Flavors

✓ GMP/SOF Certified

✓ In line with FDA CVM Guidelines

✓ Batch Tested

✓ Made in USA with Globally Sourced Ingredients

✓ Formulated by Pet Scientists

✓ No Artificial Colors or Flavors

✓ GMP/SOF Certified

✓ In line with FDA CVM Guidelines

✓ Batch Tested

✓ Made in USA with Globally Sourced Ingredients

✓ Formulated by Pet Scientists

✓ No Artificial Colors or Flavors

✓ GMP/SOF Certified

✓ In line with FDA CVM Guidelines

✓ Batch Tested

✓ Made in USA with Globally Sourced Ingredients

✓ Formulated by Pet Scientists

✓ No Artificial Colors or Flavors

✓ GMP/SOF Certified

✓ In line with FDA CVM Guidelines

✓ Batch Tested

✓ Made in USA with Globally Sourced Ingredients

✓ Formulated by Pet Scientists

Our 4 Pillars of Joint Health

Our products work together to address every aspect of joint health, offering a comprehensive solution to keep your pet active, happy, and healthy.

 

1. Protect & Support

Choose Advanced Hip & Joint Support based on your pup’s preferences and levels of discomfort. It’s highly concentrated to help protect and actively support bone & joint health.

Ideal for daily maintenance, Advanced Hip & Joint Support can also be a great option for pups who may need more intensive joint support.

Tab heading

Use this section to display different benefits or different products that are sorted by clickable tabs.

Tab heading

Use this section to display different benefits or different products that are sorted by clickable tabs.

Tab heading

Use this section to display different benefits or different products that are sorted by clickable tabs.

Why Pet Parents Choose Our Joint Formula

Our formula delivers a more complete, higher-potency blend of key joint-support ingredients in one daily serving—helping support mobility, cartilage health, and joint lubrication. Compared to other best-selling options, many products have missing or lower-dose ingredients, which can limit overall support.

That complete, clearly-dosed formula is why our product continues to be a top seller and earns strong customer reviews.

  Others
Glucosamine
MSM
Chondroitin
Hyaluronic Acid
Green Lipped Mussels
Yucca Schidigera
Vitamin C
Fish Oil

Science vs Myth

counter_1

Joint supplements are only for older dogs

The Truth:While it’s true that senior dogs benefit greatly from joint support, supplements like our Advanced Hip & Joint Support are beneficial at any age. Especially for large breeds or active dogs. Starting proactive joint care early can help support long-term health, so your pup can enjoy zoomies for years to come!

counter_2

Supplements aren't as effective as prescription medications

The Truth:Supplements including ingredients like Glucosamine, Chondroitin, MSM & Green Lipped Mussels, like our scientifically-formulated Advanced Hip & Joint Support, have been shown to help maintain joint health, reduce occasional discomfort, and support mobility. Our products work hand-in-hand with your vet’s recommendations, complementing any necessary treatments with holistic, well-researched ingredients.

counter_3

Joint supplements replace the need for exercise and a healthy diet

The Truth:Our joint supplements are an important part of a holistic approach to your dog’s well-being, but they're not a magic fix! Regular exercise and a balanced diet are key to maintaining joint health and overall vitality. Think of our supplements as the boost your dog’s joints need to stay happy and active.

counter_4

Joint supplements are just a trend

The Truth:Joint health supplements have been researched extensively. Ingredients like Glucosamine and Chondroitin are backed by scientific studies that show their potential to support cartilage health, reduce occasional joint discomfort, and help maintain mobility. They’re not just a trend - they’re part of a well-rounded care routine that can keep your dog moving comfortably.

Crafted with Love, Backed By Science

Our scientifically-proven ingredients have been scrutinized in thousands of studies, and are meticulously selected for their combined effect to enhance joint health & mobility.

  • Glucosamine

    Glucosamine is naturally produced in the body to maintain the health of the cartilage within joints. Glucosamine can help build lost cartilage by stimulating chondrocytes in the joint. It also helps maintain the integrity of the synovial fluid, enhancing mobility and reducing occasional stiffness. 

  • MSM

    Methylsulfonylmethane is a compound that is naturally produced by the body but is also found in a lot of fresh foods. MSM helps to improve blood flow to the affected areas and helps reduce discomfort and stiffness.

  • Green-Lipped Mussels

    Natural powerhouses, Green-Lipped Mussels are rich in Glucosamine, Chondroitin and Vitamins C & E, as well as antioxidants & minerals like Copper, Zinc & Selenium. They’re not only vital for your pup’s joint health, but also act as a natural solution for normal inflammatory responses.

  • Chondroitin Sulfate

    Commonly found in red meat and made by the body naturally, chondroitin can help reduce joint discomfort. It also helps stimulate Collagen AND Hyaluronic Acid production! Chondroitin has been shown to stimulate cartilage repair mechanisms and inhibit the enzymes that break down cartilage.

  • Hyaluronic Acid

    Hyaluronic Acid is naturally produced in the joint cavity in order to help lubricate the joints, making it easier to move. Supplementation of Hyaluronic Acid can help to replace the lubrication in the joints that is typically lost during the natural aging process.

  • Calcium Ascorbate (Vitamin C)

    Vitamin C has been shown to help with the absorption of Glucosamine and can improve the efficacy of Glucosamine supplementation. Vitamin C also stimulates the production of aggrecan, a component present in joint cartilage. Vitamin C is a potent antioxidant and can reduce cellular damage caused by free radicals.

  • Omega 3 EPA/DHA

    Wild Alaskan Salmon Oil is filled with Omega-3 fatty acids, polyunsaturated fats found in fish. They help promote a healthy skin and glossy fur, support joint and cardiovascular health, and enhance cognitive function.

  • Yucca Schidigera

    Yucca Schidigera is a medicinal plant that is native to Mexico. Yucca helps to relieve discomfort and inflammation caused by joint issues and aging.

    Data Doesn't Lie

    Real results from real customers.

    99%

    Saw improved mobility &

    reduced discomfort

    95%

    Would recommend us to friends

    and family

    97%

    Noticed their pups were happier

    after taking Wuffes

    Based on an independent survey conducted in 2024(n=200)

    80% of Dogs Over 8 Have Joint Problems

    Based on scientific evidence, 20% of adult dogs (over 5) and 80% of dogs over 8 suffer from painful joint issues†. Our joint chews are filled with heavily studied active ingredients that help support joint flexibility and mobility.

    Act now to enhance your pup’s joint health and maintain their mobility, well into their senior years.

    Act Now

    What to Expect With Wuffes

    Here’s some helpful information on how to take Wuffes, and what to expect in the first 90 days of consistent use.

    • Under 35lbs

      1 Soft Chew daily

    • 36-65lbs

      2 Soft Chew daily

      We recommend feeding supplements with meals.

      • saw improved mobility in 3 weeks when doubling up

      • saw improved mobility in 90 days

        *Based on an independent survey conducted in 2024 (n=200)

        Our chews are scientifically-formulated to enhance bone and joint health, so you can expect to see:

        • Maintained mobility

        • Increased eagerness to run and play

        • Visible increase in comfort

        • More ease jumping onto the couch/bed

          • With Globally Sourced Ingredients

          • Batch Tested

          • No Artificial Colors or Flavors

          • GMO, Hormone & Antibiotic free

          • GMP/SQF Certified

          • In line with FDA CVM Guidelines

            Proudly NASC-Certified

            Wuffes is now proud to display the NASC Seal, an industry mark of trust and transparency. Our certification means that every product you give to your dog meets the highest standards of safety and quality. Learn more about what this seal means for you and your pet's health.

            Tested for quality

            All supplements are rigorously tested and audited

            Trusted ingredients

            Only high-quality, traceable ingredients

            Manufactured safely

            We follow Good Manufacturing Practices for consistency.

            Trust in every tub

            The NASC Seal guarantees uncompromised quality

            Clear and transparent

            Our labels give you full transparency about ingredients.

            Scientifically formulated

            Developed with veterinary professionals to ensure top quality

            Shop Now
            • Dr. Shadi Ireifej

              DVM, DACVS
              Orthopedic Surgeon

              Dr. Shadi is a board certified small animal surgeon who received his Doctor of Veterinary Medicine degree from Cornell University. He completed his surgical residency at LIVS to become a Diplomat for the American College of Veterinary Surgeons. He currently is the owner and Chief Medical Officer of VetTriage.

            • Dr. Jennifer Repac

              DVM,  DACSMR, CVA, CCRT, CVCH

              Sports Medicine & Rehabilitation, Clinical Researcher & Professor

              Dr. Jennifer Repac received her DVM from the University of California Davis in 2009. She completed a Sports Medicine and Rehabilitation specialty internship followed by a residency at the Animal Medical Center of New York. She is now an assistant clinical professor at a leading veterinary university. Dr. Repac is a diplomate of the American College of Veterinary Sports Medicine and Rehabilitation (DACVSMR). She is also certified in canine chiropractic, Chinese herbal medicine, and acupuncture.

            • Dr. Tiffany Ruiz Da Silva

              VMD, cVMA

              Canine Nutrition

              Dr. Tiffany earned her Bachelor of Science in Biology from Brown University and her Doctor of Veterinary Medicine (VMD) from the University of Pennsylvania. With expertise in canine nutrition, her mission is to educate pet parents on the importance of nutrition for overall health, disease prevention, and mobility.

            • Dr. Joren Whitley

              Chiropractic

              Dr. Joren Whitley holds a Doctorate in Chiropractic from Parker University and a B.S. in Biochemistry and Molecular Biology from Oklahoma State University (2012). He specializes in both human and animal chiropractic care, with notable experience working with exotic species like giraffes, bobcats, bats, and snakes in Africa. His expertise spans animal sanctuaries and safaris, demonstrating a global commitment to advancing chiropractic care.

            • Dr. Erin Miscioscia

              DVM, DACVSMR, CVA

              Clinical Researcher Management of Canine Osteoarthritis & Mobility

              Dr. Miscioscia is a Clinical Assistant Professor of Integrative and Mobility Medicine. She received her DVM degree from Cornell University and completed her residency training in Integrative Medicine/ Canine Sports Medicine and Rehabilitation at the University of Florida. She's published in countless journals focusing on the efficacy of integrative therapies, especially for the management of canine osteoarthritis and mobility. She's also a Founding Member of the Pain Innovations Research Library.

              What Our Customers Are Saying

              FAQs

              Can My Pet Overdose? Can My Pet Overdose?

              If your pet devours an entire tub of Advanced Hip & Joint Support, they’ll be absolutely fine as long as the tub was designed for their weight category. Adverse effects can include vomiting, diarrhea, lethargy or gastrointestinal distress. If they’ve eaten more than one tub, or are experiencing symptoms for more than 24 hours, contact your vet for guidance.

              Where Is It Made?

              Our products are proudly made in the USA from globally sourced ingredients.

              Do Pets Need Joint Supplements?

              Joint supplements are important because they help support and maintain joint health, particularly in aging dogs or those with specific joint-related issues. They can also be beneficial for younger pups, especially larger dogs and breeds that are prone to joint issues.

              Can It Be Used With Other Supplements or Prescription Medication?

              Absolutely. As long as you follow our directions for use, our joint chews should not interfere with other supplements or prescription medications.